Search results for "Common ancestry"
showing 3 items of 3 documents
The Search for Common Origin: Homology Revisited
2018
Understanding the evolution of biodiversity on Earth is a central aim in biology. Currently, various disciplines of science contribute to unravel evolution at all levels of life, from individual organisms to species and higher ranks, using different approaches and specific terminologies. The search for common origin, traditionally called homology, is a connecting paradigm of all studies related to evolution. However, it is not always sufficiently taken into account that defining homology depends on the hierarchical level studied (organism, population, and species), which can cause confusion. Therefore, we propose a framework to define homologies making use of existing terms, which refer to …
Mouse models for multiple sclerosis: historical facts and future implications.
2011
AbstractMultiple sclerosis (MS) is an inflammatory and demyelinating condition of the CNS, characterized by perivascular infiltrates composed largely of T lymphocytes and macrophages. Although the precise cause remains unknown, numerous avenues of research support the hypothesis that autoimmune mechanisms play a major role in the development of the disease. Pathologically similar lesions to those seen in MS can be induced in laboratory rodents by immunization with CNS-derived antigens. This form of disease induction, broadly termed experimental autoimmune encephalomyelitis, is frequently the starting point in MS research with respect to studying pathogenesis and creating novel treatments. M…
On the ontogeny and orientation of the Triassic Conodont P1-element in Pseudofurnishius murcianus Van den Boogaard, 1966
2010
Successive growth stages of P1-elements in the Middle to early Late Triassic species Pseudofurnishius murcianus allows the observation of a detailed ontogeny. Besides the gradual enlargement of its curved blade and the growing number of its denticles, a small internal platform develops, eventually followed by an external one, both bearing denticles. The number of denticles on the blade and internal platform increases from five and one in the smallest specimens, respectively, to 14 and 9 in fully developed ones, whereby the distribution pattern of platform-denticles, on the inner one in particular, is of great morphological variety. For the orientation of the P1-element of P. murcianus, the …